A couple of people have mentioned that while they like the idea of offloading their site to a CDN, they're not ready to have their site look like some relic from 1999 ...
The current storm in a teacup seems to be about static vs. dynamic website design. As usual, this is a False Dichotomy ... actually, there's a whole range of options to explore.
I want to discuss some weirder things on this blog, but I think it'd be a good idea to start off with an overview of how to build a very simple HTML5- or Native App friendly architecture.